monoamine - definitie. Wat is monoamine
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Wat (wie) is monoamine - definitie

ANY ORGANIC COMPOUND BEING A MONOAMINE THAT ACTS AS A NEUROTRANSMITTER OR NEUROMODULATOR
Monaminergic neurons; Biogenic monoamines; Monoamine; Monoamine neurotransmitters; Monoamines; Monoamine neurotransmission
  • [[Dopamine]]
  •  A phylogenetic tree showing how a number of monoamine receptors are related to each other.
  • [[Norepinephrine]]
  • [[Serotonin]]

monoamine         
[?m?n??'e?mi:n]
(also monamine)
¦ noun Chemistry a compound having a single amine group in its molecule, especially one which is a neurotransmitter (e.g. serotonin, noradrenaline).
Monoamine neurotransmitter         
Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). Examples are dopamine, norepinephrine and serotonin.
Vesicular monoamine transporter         
  • A Hydrogen atom from the inside of the vesicle binds, inducing a conformational change in the transporter
  • The monoamine is released inside the vesicle and the two hydrogen atoms are released into the cytosol and the transport process starts over again.
  • A second hydrogen atom binds from inside the vesicle to the transporter inducing another change
  • The conformational change induced by the hydrogen atom binding enables the monoamine binding to the active transport site
FAMILY OF TRANSPORT PROTEINS
Vesicular Monoamine Transporter; VMAT; Vesicular monoamine transport proteins; Vesicular amine transporter; Vesicular monoamine transporters; Vesicle monoamine transporter; Vesicular monoamine transporter inhibitor; Vesicular monoamine transporter inhibitors; VMAT inhibitors; VMAT inhibitor
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports monoamine neurotransmitters – such as dopamine, serotonin, norepinephrine, epinephrine, and histamine – into the vesicles, which release the neurotransmitters into synapses as chemical messages to postsynaptic neurons.

Wikipedia

Monoamine neurotransmitter

Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). Examples are dopamine, norepinephrine and serotonin.

All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, and tryptophan by the action of aromatic amino acid decarboxylase enzymes. They are deactivated in the body by the enzymes known as monoamine oxidases which clip off the amine group.

Monoaminergic systems, i.e., the networks of neurons that use monoamine neurotransmitters, are involved in the regulation of processes such as emotion, arousal, and certain types of memory. It has also been found that monoamine neurotransmitters play an important role in the secretion and production of neurotrophin-3 by astrocytes, a chemical which maintains neuron integrity and provides neurons with trophic support.

Drugs used to increase or reduce the effect of monoamine neurotransmitters are used to treat patients with psychiatric and neurological disorders, including depression, anxiety, schizophrenia and Parkinson's disease.

Voorbeelden uit tekstcorpus voor monoamine
1. At various points throughout the study, levels of the gene monoamine oxidase A – which is associated with antisocial behaviour – were measured.
2. Earlier studies have shown that low levels of brain chemicals such as serotonin and monoamine oxidase A, also known as MAOA, are linked to violent behaviour in humans and animals.